Immunology Structure and Evolution

Human cGAS

PDB: 4KM5

Ancient STING Receptors

PDB: 5CFL, 5CFM, 5CFN, 5CFO, 5CFP,
5CFQ, 5CFR

V. cholerae cGAS Homolog (DncV)

PDB: 4TXY, 4TXZ, 4TY0

Research Collaborations

With Amy Lee, Jaime Cate
Lee Lab – Brandeis University

Protein Translation
eIF3d Cap-Recognition Domain

PDB: 5K4B, 5K4C, 5K4D

With James Nuñez
Doudna Lab – UC-Berkeley

CRISPR Bacterial Immunity
E. coli Cas1–Cas2 Complex

PDB: 4P6I

With James Nuñez, Lucas Harrington
Doudna Lab – UC-Berkeley

CRISPR Bacterial Immunity
E. coli Cas1–Cas2–dsDNA Complex

PDB: 5DS4, 5DS5, 5DS6

With Kevin Doxzen, Emine Kaya
Doudna Lab – UC-Berkeley

Atypical Argonaute Complex
M. piezophila Argonaute–ssRNA

PDB: 5I4A

With Lucas Harrington, Kevin Doxzen
Doudna Lab – UC-Berkeley

CRISPR Bacterial Immunity
NmeCas9–AcrIIC1 Inhibitory Complex

PDB: 5VGB

With Katjuša Brejc
Meyer Lab – UC-Berkeley

Chromatin H4K20 Modification
C. elegans DPY-21 Demethylase

PDB: 5UQD

© 2017, Kranzusch Lab