Recent Publications

Ancient origin of cGAS-STING reveals mechanism of universal 2′,3′ cGAMP signaling.
Kranzusch PJ*, Wilson SC*, Lee ASY, Berger JM, Doudna JA, Vance RE.
Molecular Cell. 2015; 59(6), 891–903. (Link)

Structure-guided reprogramming of human cGAS dinucleotide linkage specificity.
Kranzusch PJ, Lee ASY, Wilson SC, Solovykh MS, Vance RE, Berger JM, Doudna JA.
Cell. 2014; 158(5), 1011–1021. (Link)

Structure of human cGAS reveals a conserved family of second-messenger enzymes in innate immunity.
Kranzusch PJ, Lee ASY, Berger, JM, Doudna JA.
Cell Reports. 2013; 3(5), 1362-1368. (Link)


Philip J. Kranzusch, Ph.D.
Assistant Professor of Microbiology and Immunobiology
Harvard Medical School
Dana-Farber Cancer Institute

© 2018, Kranzusch Lab