Recent Publications

A DNA-gated molecular guard controls bacterial Hailong anti-phage defence.
Tan JMJ, Melamed S, Cofsky JC, Syangtan D, Hobbs SJ, Marmol JD, Jost M, Kruse AC, Sorek R, Kranzusch PJ.
Nature. 2025; Advanced online publication 4/30/2025. (Link).

Animal and bacterial viruses share conserved mechanisms of immune evasion.
Hobbs SJ, Nomburg J, Doudna JA, Kranzusch PJ.
Cell. 2024; 187(20), 5530–5539. (Link). 

Structural basis of Gabija anti-phage defence and viral immune evasion.
Antine SP, Johnson AG, Mooney SE, Leavitt A, Mayer ML, Yirmiya E, Amitai G, Sorek R, Kranzusch PJ.
Nature. 2024; 625(7994), 360–365. (Link). 

cGLRs are a diverse family of pattern recognition receptors in animal innate immunity.
Li Y, Slavik KM, Toyoda HC, Morehouse BR, de Oliveira Mann CC, Elek A, Levy S, Wang Z, Mears KS, Liu J, Kashin D, Guo X, Mass T, Sebé-Pedrós A, Schwede F, Kranzusch PJ.
Cell. 2023; 186(15), 3261–3276. (Link).