Recent Publications

cGLRs are a diverse family of pattern recognition receptors in animal innate immunity.
Li Y, Slavik KM, Toyoda HC, Morehouse BR, de Oliveira Mann CC, Elek A, Levy S, Wang Z, Mears KS, Liu J, Kashin D, Guo X, Mass T, Sebé-Pedrós A, Schwede F, Kranzusch PJ.
Cell. 2023; 186(15), 3261–3276. (Link).

Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.
Duncan-Lowey B*, Tal N*, Johnson AG, Rawson SR, Myer ML, Doron S, Millman A, Melamed S, Fedorenko T, Kacen A, Brandis A, Mehlman T, Amitai G, Sorek R#, Kranzusch PJ#.
Cell. 2023; 186(5), 987–998. (Link). (*co-first, #co-corresponding)

Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity.
Hobbs SJ, Wein T, Lu A, Morehouse BR, Schnabel J, Leavitt A, Yirmiya E, Sorek R, Kranzusch PJ.
Nature. 2022; 605(7910), 522–526. (Link).

Bacterial gasdermins reveal an ancient mechanism of cell death.
Johnson AG*, Wein T*, Mayer ML, Duncan-Lowey B, Yirmiya E, Oppenheimer-Shaanan Y, Amitai G,
Sorek R#, Kranzusch PJ#.
Science. 2022; 375(6577), 221–225. (Link). (*co-first, #co-corresponding)