Recent Publications

Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.
Duncan-Lowey B*, Tal N*, Johnson AG, Rawson SR, Myer ML, Doron S, Millman A, Melamed S, Fedorenko T, Kacen A, Brandis A, Mehlman T, Amitai G, Sorek R#, Kranzusch PJ#.
Cell. 2023; 186(5), 987–998. (Link). (*co-first, #co-corresponding)

Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity.
Hobbs SJ, Wein T, Lu A, Morehouse BR, Schnabel J, Leavitt A, Yirmiya E, Sorek R, Kranzusch PJ.
Nature. 2022; 605(7910), 522–526. (Link).

Bacterial gasdermins reveal an ancient mechanism of cell death.
Johnson AG*, Wein T*, Mayer ML, Duncan-Lowey B, Yirmiya E, Oppenheimer-Shaanan Y, Amitai G,
Sorek R#, Kranzusch PJ#.
Science. 2022; 375(6577), 221–225. (Link). (*co-first, #co-corresponding)

cGAS-like receptors sense RNA and control 3′2′-cGAMP signalling in Drosophila.
Slavik KM, Morehouse BR, Ragucci AE, Zhou W, Ai X, Chen Y, Li L, Wei Z, Bähre H, König M, Seifert R, Lee ASY, Cai H, Imler JL, Kranzusch PJ.
Nature. 2021; 597(7874), 109–113. (Link).