Recent Publications

Nuclease-NTPase antiphage defence systems use conserved molecular features to control bacterial immunity.
Ragucci AE*, Antine SP*, Leviss EM, Mooney SE, Garcia JM, Shyrokova L, Hauryliuk V, Lee ASY, Kranzusch PJ.
Nature Microbiology. 2026; 11(5):1424–1436. (*co-first) (Link).

Nucleotide signals coordinate activation and inhibition of bacterial immunity.
Yamaguchi S, Fernandez SG, Wassarman DR, Lüders M, Schwede F, Kranzusch PJ.
Nature. 2026; 652(8111), 978–985. (Link).

Deazaguanylation is a nucleobase-protein conjugation required for type IV CBASS immunity.
Wassarman DR, Pfaff P, Paulo JA, Gygi SP, Shokat KM, Kranzusch PJ.
Science. 2025; 389(6767), 1347–1352. (Link).

Animal and bacterial viruses share conserved mechanisms of immune evasion.
Hobbs SJ, Nomburg J, Doudna JA, Kranzusch PJ.
Cell. 2024; 187(20), 5530–5539. (Link).